What is the recommended dosage of aspirin for chronic use in stroke prevention?

The recommended dosage of aspirin for chronic use in stroke prevention is 81 mg. This lower dose is effective for reducing the risk of subsequent strokes and cardiovascular events while minimizing the risk of adverse effects, such as gastrointestinal bleeding.

In practice, the use of low-dose aspirin, typically 81 mg, has been supported by clinical guidelines due to its ability to inhibit platelet aggregation effectively without the increased risk of bleeding associated with higher doses. The 81 mg dose balances efficacy and safety, making it a standard recommendation for patients at risk of stroke or those with a history of cerebrovascular disease.

Higher doses, such as 100 mg or 325 mg, are generally not necessary for stroke prevention and could increase the likelihood of side effects without providing additional benefit in terms of stroke risk reduction. The lower dose has been extensively studied and proven to be sufficient for maintaining cardiovascular health and preventing thrombotic events.