What level of calcium indicates hyperparathyroidism?

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In hyperparathyroidism, elevated levels of calcium in the blood are typically observed due to increased secretion of parathyroid hormone (PTH), which regulates calcium levels. A calcium level above 11 mg/dL is commonly associated with primary hyperparathyroidism, but when it exceeds 13 mg/dL, it is considered a significant indicator of this condition.

Levels above 13 mg/dL suggest severe hypercalcemia and are distinctly linked to hyperparathyroidism, as the body is unable to handle the high levels of calcium effectively, leading to symptoms and complications.

While levels above 10 mg/dL may indicate elevated calcium, they are not definitive for hyperparathyroidism, and might occur in various other conditions. Similarly, levels above 15 mg/dL indicate a severe state but represent a more acute or severe form of hypercalcemia than what is typically seen in the chronic state of primary hyperparathyroidism. Thus, identifying hyperparathyroidism is best recognized at calcium levels greater than 13 mg/dL, aligning with medical definitions and practice guidelines.

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