Which drug class is commonly used to alleviate pain in lateral epicondylitis?

The use of non-steroidal anti-inflammatory drugs (NSAIDs) is well-documented in the management of conditions like lateral epicondylitis, commonly known as "tennis elbow." This condition involves inflammation of the tendons that attach to the lateral epicondyle of the humerus, causing pain and discomfort in the elbow and forearm.

NSAIDs are effective because they target both pain and the underlying inflammation. By inhibiting the enzymes involved in the production of prostaglandins, which are compounds that promote inflammation, pain, and fever, NSAIDs provide symptomatic relief, making them a first-line treatment option for lateral epicondylitis. Moreover, they can help improve range of motion and facilitate rehabilitation exercises necessary for recovery.

In contrast, other drug classes like opioids are primarily used for severe pain and carry a risk of dependency and side effects; corticosteroids can be injected for more severe inflammation but come with potential adverse effects when used long-term, and antibiotics are used to treat infections rather than inflammatory pain disorders. This makes NSAIDs the most appropriate choice for managing pain associated with lateral epicondylitis.