Which of the following is a sign of insulin resistance that can be related to Down syndrome?

Increased blood sugar after meals is indeed a sign of insulin resistance, which can be particularly relevant in individuals with Down syndrome. Insulin resistance occurs when the body's cells become less sensitive to insulin, leading to impaired glucose uptake. Consequently, after consuming a meal, the glucose from the food remains in the bloodstream longer than it should, causing a rise in blood sugar levels.

This phenomenon is significant in the context of Down syndrome because individuals with this condition often exhibit a higher prevalence of metabolic disorders, including obesity and diabetes, which are closely linked to insulin resistance. Therefore, the occurrence of elevated blood sugar levels after eating is a clear indicator of this resistance.

In contrast, decreased blood sugar levels would suggest effective glucose management and not resistance; improved glucose metabolism indicates that the body is adequately processing glucose, opposing the concept of resistance; and stable insulin production would imply proper insulin function without the issues associated with insulin resistance. Thus, the choice reflecting increased blood sugar after meals is the correct representation of insulin resistance in this scenario.