Which of the following treatments is indicated for severe symptoms of rosacea?

Oral antibiotics are indicated for the treatment of severe symptoms of rosacea primarily because they address the inflammatory component of the condition. Rosacea can often present with persistent facial redness, papules, and pustules, which are similar to acne but have different underlying mechanisms. In cases where topical treatments are not sufficient, oral antibiotics, particularly tetracycline-class medications such as doxycycline or minocycline, help to reduce inflammation and bacterial colonization associated with rosacea.

In addition to their anti-inflammatory properties, oral antibiotics can also decrease the population of skin bacteria that may contribute to the flare-ups. The systemic nature of these medications enables them to effectively reach all areas of the skin, providing better results for individuals experiencing significant or widespread symptoms.

Hydrating lotions, topical corticosteroids, and antihistamines may not target the specific inflammatory processes involved in rosacea. While hydrating lotions can provide skin barrier support and enhance moisture, they do not directly address inflammation. Topical corticosteroids may worsen rosacea in some cases, as they can lead to a rebound effect or trigger further irritation upon withdrawal. Antihistamines can alleviate allergy symptoms, but they do not have a role in treating the underlying issues of rosacea. Thus, oral antibiotics remain the