Which symptom is NOT typically associated with Kawasaki disease?

Kawasaki disease is primarily characterized by a specific set of symptoms that include high fever lasting more than five days, rash, conjunctivitis, changes in the lips and oral cavity (such as cracked lips and strawberry tongue), cervical lymphadenopathy, and extremity changes like edema and peeling skin.

The presence of peeling skin and edema of the hands and feet are both significant manifestations of Kawasaki disease, often occurring as part of the later stages of the condition. The fever is a hallmark symptom that is usually present from the onset of the disease.

In contrast, unilateral headache is not a recognized symptom of Kawasaki disease. While headaches can occur in various conditions, they do not align with the classic presentation of Kawasaki disease and are not typically reported as a direct symptom of this illness. The correct choice highlights a symptom that does not fit within the expected clinical framework for Kawasaki disease.